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Biomedical Research and Research Training

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This federal aid program is managed by:

National Institutes of Health, Department of Health and Human Services


The National Institute of General Medical Sciences supports research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment and prevention. NIGMS-funded researchers seek to answer important scientific questions in fields such as cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, bioinformatics, computational biology, selected aspects of the behavioral sciences and specific cross-cutting clinical areas that affect multiple organ systems. NIGMS also provides leadership in training the next generation of scientists and increasing the diversity of the scientific workforce to assure the vitality and continued productivity of the research enterprise.

Funding obligations:

(Project Grants) FY 09 $1,911,377,000; FY 10 est $1,960,208,000; FY 11 est $2,007,549,000

Uses and Use Restrictions:

NIGMS is organized into divisions and a center that support research and research training in a range of scientific fields. One division has the specific mission of increasing the number of biomedical and behavioral scientists who are members of underrepresented groups. Major areas in which these units fund research are listed below their names. Division of Cell Biology and Biophysics: analytical and separation techniques biophysical properties of proteins and nucleic acids cell organization, motility and division cellular imaging membrane structure and function molecular biophysics single-molecule biophysics and nanoscience spectroscopic techniques structural biology structural genomics and proteomics Division of Genetics and Developmental Biology: chromosome organization and mechanics developmental biology and genetics DNA replication, recombination and repair epigenetics extrachromosomal inheritance mechanisms of mutagenesis neurogenetics and the genetics of behavior population genetics, evolution and the genetics of complex traits protein synthesis regulation of cell growth, cell division, cell death and differentiation RNA transcription and processing stem cell biology Division of Pharmacology, Physiology, and Biological Chemistry: anesthesiology biochemistry bioenergetics bio-organic and bio-inorganic chemistry biotechnology and metabolic engineering drug absorption, distribution, metabolism, excretion and predictive toxicology enzymology glycochemistry and glycobiology molecular immunobiology pharmacogenetics/pharmacogenomics pharmacology and clinical pharmacology physiology synthetic and medicinal chemistry trauma and burn injury wound healing Division of Minority Opportunities in Research: undergraduate student training and development post-baccalaureate research education predoctoral research postdoctoral research and teaching skill development faculty development faculty research efficacy of interventions research Center for Bioinformatics and Computational Biology: biomedical software development cell and molecular modeling and simulation computational genomics database design and enhancement high-throughput data analysis systems biology.

Examples of Funded Projects:

Fiscal Year 2010: No Current Data Available Fiscal Year 2011: No Current Data Available Fiscal Year 2012: No Current Data Available

Program Accomplishments:

Fiscal Year 2010: No Current Data Available Fiscal Year 2011: No Current Data Available Fiscal Year 2012: No Current Data Available

Types of Assistance:


Range and Average of Financial Assistance:

$20,000 to $10,000,000.

Length and Time Phasing of Assistance:

Almost all awards are made for at least 1 year, with additional support (up to 4 more years) depending on the recommendation of the scientific review group, the national advisory council, successful annual performance and availability of funds. See the following for information on how assistance is awarded/released: varies by program, always on an annual basis.

Applicant Eligibility:

NIGMS trainees must be U.S. citizens, non-citizen nationals or permanent residents.

Beneficiary Eligibility:

Any nonprofit or for-profit organization, company or institution engaged in biomedical research.

Award Procedure:

All accepted applications are reviewed for scientific merit by an appropriate initial review group and by a national advisory council. National Research Service Award (NRSA) applications for the support of individual fellows and other applications requesting less than $50,000 direct costs per year are not reviewed by the council. All approved applications compete for available funds on the basis of scientific merit and program emphasis.

Contact Info for Headquarters Office:

Susan J. Athey, 45 Center Drive MSC6200, Bethesda, Maryland 20892 Email: Phone: (301) 496-7301 Fax: (301) 402-0224.

Website Address:

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